ABSTRACT. Disseminated intravascular coagulation (DIC) is an acquired disorder in which normal hemostatic balance is disturbed. There. Disseminated intravascular coagulation, or DIC, is a complicated condition that can occur when someone has severe sepsis or septic shock. Disseminated intravascular coagulation (DIC) is a serious disorder in which the proteins that control blood clotting become overactive.

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Disseminated intravascular coagulation (DIC): MedlinePlus Medical Encyclopedia

When you are injured, proteins in the blood that form blood clots travel to the injury site to help stop bleeding. If these proteins become abnormally active throughout the body, you could develop DIC. The underlying cause is foagulation due to inflammation, infection, or cancer. Dksseminated some cases of DIC, small blood clots form in the blood vessels.

Some of these clots can clog the vessels and cut off the normal blood supply to organs such as the liver, brain, or kidneys. Lack of blood flow can damage and cause major injury to the organs. In other cases of DIC, the clotting proteins in your blood are consumed. When this happens, you may have a high risk of serious bleeding, even from a minor injury or without coagluation.


You may also have bleeding that starts spontaneously on its own. The disease can also cause your healthy red blood cells to fragment and break up when they travel through the small vessels that are filled with clots.

There is no specific treatment for DIC. The goal is to determine and treat the underlying cause of DIC.

Disseminated intravascular coagulation (DIC)

Goldman L, Schafer AI, eds. Review provided by VeriMed Healthcare Network.

Disseminated intravascular coagulation DIC. Risk factors for DIC include: Blood transfusion reaction Cancer, especially certain types of leukemia Inflammation of the pancreas pancreatitis Infection in the blood, especially by bacteria or fungus Liver disease Pregnancy complications such as placenta that is left behind after delivery Recent surgery or anesthesia Severe tissue intravaschlar as in burns and head injury Large hemangioma a blood vessel that is not formed properly.

Symptoms of DIC may include any of the following: Bleeding, from many sites in the body Blood clots Bruising Drop in blood pressure Iintravascular of breath Confusion, memory loss or change of behavior Fever. You may have any of the following tests: Supportive treatments may include: Plasma transfusions to replace blood clotting factors if a large amount of bleeding is occurring.


Disseminated intravascular coagulation – Wikipedia

Blood thinner medicine heparin to prevent blood clotting if a large amount of clotting is occurring. Outcome depends on what is causing the disorder. DIC can be life threatening. Complications from DIC may include: Bleeding Lack of blood flow to the arms, legs, or vital organs Stroke. When to Contact a Medical Professional.

Sepsis and DIC

Go to the emergency room or call if you have bleeding that does not stop. Get prompt treatment for conditions known to bring on this disorder. Blood clot formation Meningococcemia on the calves Blood clots.

Bleeding Disorders Read more. Blood Clots Read more.