Characterisation. The drug substance is an aptamer, meaning it is the secondary structure (i.e. folding) of the Macugen is manufactured by dissolving pegaptanib sodium into a physiologically-compatible solution. speculum was inserted. Drug interaction studies have not been conducted with Macugen. Pegaptanib is metabolised by .. Package Leaflet: Information for the patient. Macugen mg . therefore, inaccurately states that pegaptanib (i.e., the drug) contains includes safety information and the ability to print the Package Leaflet.

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Pegaptanib is a prescription medication used to treat wet age-related macular degeneration AMD. This medication is available in an injectable form to be given directly into the eye by a healthcare professional once every packagd weeks. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Serious side effects have been reported with pegaptanib. This is not a complete list of pegaptanib packagw effects.

Call your doctor for medical advice about side effects. No drug interactions have been studied by the manufacturer.

However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported. Pegaptanib can cause blurred vision and dizziness. Medications can interact with certain foods. In some cases, this may be harmful and macugsn doctor may advise you to avoid certain foods. In macuyen case of pegaptanib, there are no specific foods that you must exclude from your diet when receiving this medication.

Before taking pegaptanib, tell your doctor about all of your medical conditions. Especially tell your doctor if you. It is not known if pegaptanib crosses into human milk.


Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication.

Before the treatment is given your eye doctor may ask you to use antibiotic eye drops, or to wash your eyes carefully. Please follow these instructions carefully.

After each injection your doctor might prescribe antibiotic eye drops or another type of antibiotic treatment to prevent an eye infection. The recommended dose of Macugen pegaptanib is 0. Pegaptanib treats an eye disease called macular degeneration. Can cause blurred vision and dizziness. Do not drive macuten operate heavy machinery until you know how this medication affects you.

Patient Ratings for Pegaptanib. How was your experience with Pegaptanib? First, a little about macuegn Male Female.

What tips would you provide a friend before taking Pegaptanib?

How well did Pegaptanib work for you? Did you experience many side effects while taking this drug? How likely would you be to recommend Pegaptanib to a friend? Pegaptanib Cautionary Labels Back to Top. Uses of Pegaptanib Back to Top. Pegaptanib Brand Names Back to Top. Pegaptanib may be found in some form under the following brand names: Pegaptanib Drug Class Back to Top. Pegaptanib is part of the drug class: Side Effects of Pegaptanib Back to Top.

Tell your doctor if you have any side effect that bothers you or that does not go away. Pegaptanib Interactions Back to Top.

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Pegaptanib Precautions Back to Top. Serious side effects have been reported with pegaptanib including the following: Endophthalmitis inflammation of the inner coats of the eye due to an infection. Increases in intraocular pressure. Increases in the pressure inside the eye have been seen within 30 minutes of injection with pegaptanib. Your doctor should monitor you appropriately.


MACUGEN – (pegaptanib sodium injection)

Anaphylaxis severe allergic reaction: Do not take pegaptanib if you: Pegaptanib Food Interactions Back to Top. Inform MD Back to Top. Pegaptanib and Pregnancy Back to Top.

Tell your doctor if you are pregnant or plan to become pregnant. The FDA categorizes medications based on safety for use during pregnancy. Five categories – A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Pegaptanib and Lactation Back to Top. Tell your doctor if you are breastfeeding or plan to breastfeed. Pegaptanib Usage Back to Top. If you miss a dose, be sure to make a follow up appointment. Pegaptanib Dosage Back to Top. Pegaptanib Overdose Back to Top.

If pegaptanib is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.


Other Requirements Back to Top. Keep all appointments with your doctor. Your doctor will need to examine your eyes to see if you are developing serious side effects during the week following the injection.